The hospital is situated in Hospital Street in Uniondale, Western Cape. Nearby main roads are the R339 and the N9 highway to the North of the hospital. Uniondale is located 114km North-East of George and 117km East of Oudtshoorn.
Uniondale hospital is a public hospital and therefore services are free to pregnant and breastfeeding women, as well as children under the age of six years old and pensioners. Other patients are charged a consultation and/or admission fee.