The hospital is located in Mati Road, New Brighton, Port Elizabeth, Eastern Cape. Mati Road is off the R75 (Commercial Road), close to the N2 highway. New Brighton is surrounded by Kwazakele, Sidwell and Algoa Park Suburbs in Port Elizabeth.
Empilweni TB Hospital is a provincial hospital, and services are free to pregnant and breastfeeding women as well as children under the age of six years old. Other citizens are charged according to a sliding scale depending on their income.
- Accredited ART site with X-Ray facilities.